Korean J Med.
2016 Aug;91(1):75-78. 10.3904/kjm.2016.91.1.75.
Acute Myeloid Leukemia with the 11q23 Rearrangement in a Patient with Klinefelter Syndrome
- Affiliations
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- 1Department of Internal Medicine, Wonkwang University School of Medicien, Iksan, Korea. mdshim@wku.ac.kr
- 2Department of Laboratory Medicine, Wonkwang University School of Medicien, Iksan, Korea.
- KMID: 2345589
- DOI: http://doi.org/10.3904/kjm.2016.91.1.75
Abstract
- Klinefelter syndrome is usually characterized by eunuchoidism, gynecomastia, small testes, infertility, elevated gonadotropins, mental retardation, and a constitutional extra X chromosome. Several reports have suggested an association between leukemia and Klinefelter syndrome, although two cohort studies failed to show a clear association between the two. We report the first Korean case of acute myeloid leukemia with the 11q23 rearrangement in a 27-year-old man with Klinefelter syndrome.
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