Korean Circ J.  2016 Jul;46(4):530-535. 10.4070/kcj.2016.46.4.530.

Atrial Electromechanical Coupling in Patients with Lichen Planus

• Yaman M
• Arslan U
• Beton O
• Asarcıklı LD
• Aksakal A
• Dogdu O

• KMID: 2344428
• DOI: http://doi.org/10.4070/kcj.2016.46.4.530

Abstract

BACKGROUND AND OBJECTIVES
A chronic inflammatory disease, lichen planus may cause disturbance of atrial electromechanical coupling and increase the risk of atrial fibrillation. The aim of this study was to evaluate atrial electromechanical delay with both electrocardiography (ECG) and echocardiography in patients with lichen planus (LP).
SUBJECTS AND METHODS
Seventy-two LP patients (43 males [59.7%], mean age: 44.0±16.7 years) were enrolled in this cross-sectional case-control study. The control group was selected in a 1:1 ratio from 70 patients in an age and sex matched manner. P wave dispersion was measured by ECG to show atrial electromechanical delay. All of the patients underwent transthoracic echocardiography for measuring inter- and intra-atrial electromechanical delays.
RESULTS
The baseline characteristics of the patients and the control group were similar except for the presence of LP. P-wave dispersion measured by ECG was significantly higher in patients with LP (p<0.001). Patients with LP had significantly prolonged intra- and interatrial electromechanical delays when compared to the control group (p<0.001). In addition, all of these variables were significantly correlated with high sensitive C-reactive protein (hsCRP) levels.
CONCLUSION
Atrial electromechanical coupling, which is significantly correlated with increased hsCRP levels, is impaired in patients with LP.

Keyword

Lichen planus; Echocardiography; Electrocardiography

MeSH Terms

Atrial Fibrillation
C-Reactive Protein
Case-Control Studies
Echocardiography
Electrocardiography
Humans
Lichen Planus*
Lichens*
Male
C-Reactive Protein

Figure

• 

  Fig. 1 Measurement of the PA interval with tissue Doppler imaging, which denotes time interval from the onset of P wave on the surface electrocardiogram to the beginning of the late diastolic wave (Am wave). PA: P-wave to the beginning of A-wave on surface ECG.

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