Korean J Radiol.  2015 Dec;16(6):1262-1265. 10.3348/kjr.2015.16.6.1262.

Pulmonary Actinomycosis Imitating Lung Cancer on ¹⁸F-FDG PET/CT: A Case Report and Literature Review

Affiliations
  • 1Department of Nuclear Medicine, The First Affiliated Hospital, Sichuan Medical University, Luzhou, Sichuan 64600, China. chenyue5523@126.com
  • 2Department of Radiology, The First Affiliated Hospital, Sichuan Medical University, Luzhou, Sichuan 64600, China.

Abstract

Here we report a case of 41-year-old man with a soft tissue density mass at right upper lung and palpable abscesses at right upper backside and right wrist. ¹â¸F-fluorodeoxyglucose positron emission tomography/computed tomography demonstrated a 7.8 × 5.0 cm mass with soft-tissue density in the upper lobe of the right lung with high metabolic activity. The infiltrative mass extended to adjacent chest wall soft tissue. Final diagnosis of pulmonary actinomycosis with multiple abscesses was made. The patient responded well to antibiotics treatment.

Keyword

Actinomycosis; Multiple abscesses; ¹⁸F-FDG PET/CT

MeSH Terms

Abscess
Actinomycosis/*diagnosis/drug therapy/microbiology
Adult
Anti-Bacterial Agents/therapeutic use
Diagnosis, Differential
Fluorodeoxyglucose F18/chemistry
Humans
Lung Diseases/*diagnosis/drug therapy/microbiology
Lung Neoplasms/pathology
Male
*Positron-Emission Tomography
Tomography, X-Ray Computed
Anti-Bacterial Agents
Fluorodeoxyglucose F18

Figure

  • Fig. 1 41-year-old man with pulmonary actinomycosis imitating lung cancer on 99mTc-MDP bone scintigraphy. A. Posterior. B. Uptake of radiotracer is increased at right third and fourth posterior ribs (small black arrows, A) and right multiple carpal bones (large black arrow, A).

  • Fig. 1 41-year-old man with pulmonary actinomycosis imitating lung cancer with whole body 18F-FDG PET/CT scan. C. Maximum intensity projection showing mass at upper lobe of right lung and peripheral daughter lesions. D. 7.8 × 5.0 cm soft-tissue density mass is demonstrated. Mass has intense 18F-FDG accumulation (SUVmax = 13.3). E, F. Some opaque mottled shadows with 18F-FDG uptake are distributed in multiple lobes of right lung and inferior lobe of left lung. G-I. Infiltrative mass extended to adjacent chest wall, thoracodorsal muscle, and subcutaneous dermal tissues. SUVmax = maximal standardized uptake value, 18F-FDG PET/CT = 18F-fluorodeoxyglucose positron emission tomography/computed tomography

  • Fig. 1 41-year-old man with pulmonary actinomycosis imitating lung cancer with pathological analysis. J. Pathological result (hematoxylin-eosin staining, × 100) revealed chronic inflammation with proliferation of fibrotic granulation tissue.


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