J Korean Neurol Assoc.
2010 Nov;28(4):323-325.
Bilateral Optic Neuritis as the First Manifestation of Systemic Lupus Erythematosus Associated With Neuromyelitis Optica
- Affiliations
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- 1Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea. jisookim@snu.ac.kr
- 2Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
- 3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
Abstract
- Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous system that is characterized by severe episodes of transverse myelitis and optic neuritis. Aquaporin-4-specific autoantibody (NMO IgG) is the marker of NMO. We report herein a 28-year-old woman with systemic lupus erythematosus (SLE) that manifested with bilateral optic neuritis. She had NMO IgG in addition to clinical and serologic characteristics of SLE. This is the first report of a patient with SLE and NMO IgG that manifested with sequential bilateral optic neuritis.
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