J Korean Neurol Assoc.  2005 Apr;23(2):264-267.

Multiple Germ Cell Tumors Manifesting as Anterior Hypothalamic and Pretectal Syndromes

Affiliations
  • 1Department of Neurology, Seoul National University College of Medicine, Seoul, Korea. jisookim@snu.ac.kr
  • 2Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Neurology, Armed Forces Capital Hospital, Seongnam, Korea.

Abstract

A 21-year-old man presented with vertical diplopia and subsequently developed heat-dissipation deficit, central diabetes insipidus, light-near dissociation of the pupillary responses, convergence-retraction nystagmus, and mild upgaze limitation. These were consistent with the anterior hypothalamic and pretectal syndromes. Gadolinum-enhanced MRI revealed lesions, involving the suprasellar and pretectal areas, which were consistent with multiple germ cell tumors. The rare combination of anterior hypothalamic and pretectal syndromes may be manifestation of multiple germ cell tumors and require careful evaluation of these areas using gadolinum-enhanced MRI.

Keyword

Suprasellar; Pretectal syndrome; Germ cell tumor

MeSH Terms

Diabetes Insipidus, Neurogenic
Diplopia
Germ Cells*
Humans
Magnetic Resonance Imaging
Neoplasms, Germ Cell and Embryonal*
Young Adult
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