J Korean Neurol Assoc.  2001 Jul;19(4):413-416.

Intravascular Lymphomatosis in Central Nervous System

Affiliations
  • 1Department of Neurology, Ajou University School of Medicine.
  • 2Department of Pathology, Ajou University School of Medicine.

Abstract

Intravascular lymphomatosis (IL) is a variant of non-Hodgkin's lymphoma with an predilection for the CNS. Most cases are not diagnosed until postmortem. IL is characterized by neoplastic proliferation of lymphoid cells within the lumen of small veins and arteries with minimal involvement of the parenchyma. We experienced a 62-year-old woman who presented with seizure and fever associated with anemia, elevated LDH and beta 2-microglobulin without systemic involvement. This report illustrates the diagnostic challenge of this rare disorder with a grave prognosis. (J Korean Neurol Assoc 19(4):413~416, 2001)

Keyword

Intravascular lymphomatosis; beta 2-Microglobulin; Lactate dehydrogenase

MeSH Terms

Anemia
Arteries
beta 2-Microglobulin
Central Nervous System*
Female
Fever
Humans
L-Lactate Dehydrogenase
Lymphocytes
Lymphoma, Non-Hodgkin
Middle Aged
Prognosis
Seizures
Veins
L-Lactate Dehydrogenase
beta 2-Microglobulin
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