J Korean Neurol Assoc.  1998 Oct;16(5):728-731.

A case of neurosarcoidosis without systemic involvement

Affiliations
  • 1Department of Neurology, Keimyung University School of Medicine.

Abstract

Sarcoidosis is a multisystem disorder of unknown cause. The involvement of the nervous system occurs 5% to 27% of patients with sarcoidosis, and neurosarcoidosis without systemic involvement is rare and difficult to diagnose. We present a case of 58-year-old woman with clinical features of multiple cranial and peripheral polyneuropathy with noncaseating granulomatous inflammation. Extensive testing for occult systemic sarcoidosis was negative. Sural nerve biopsy showed several perineural noncaseous granulomatous inflammation with prominent epithelioid cells. Oral steroid therapy led to some improvement. We report a patient with multiple cranial and peripheral polyneuropathy without systemic involvement, suspected sarcoidosis.

Keyword

sarcoidosis; cranial neuropathy; peripheral polyneuropathy; noncaseous granulomatous inflammation

MeSH Terms

Biopsy
Cranial Nerve Diseases
Epithelioid Cells
Female
Humans
Inflammation
Middle Aged
Nervous System
Polyneuropathies
Sarcoidosis
Sural Nerve
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