J Korean Neurol Assoc.
1997 Feb;15(1):233-236.
A case of aseptic meningitis following intrathecal administration of methotrexate
- Affiliations
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- 1Department of Neurology, School of Medicine, Catholic University of TaeguHyosung.
Abstract
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Methotrexate(MTX) is currently one of the most important antineoplastic drugs used in chemotherapy. Intrathecal(IT) MTX is widely used to treat or prevent meningeal leukemia and lymphoma. Aseptic meningitis following IT MTX is not uncommon, but not reported frequently in neurological field. We report a case of aseptic meningitis following IT MTX in acute lymphocytic leukemia.