J Korean Neurol Assoc.
1997 Feb;15(1):137-151.
Creutzfeldt-jakob disease
- Affiliations
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- 1Department of Neurology, Samsung Medical Center.
- 2Department of Neurosurgery, Samsung Medical Center.
- 3Department of Diagnostic Pathology, Samsung Medical Center.
- 4Department of Nuclear Medicine, Samsung Medical Center.
- 5Department of Neurology, Seoul National University.
- 6Department of Neurology, Eul Ji Medical Center.
Abstract
- We present three neuropathologically-verified and two clinically-probable cases of Creutfeldt Jakob disease. All five had nonspecific prodromal complaints or symptoms prior to overt neurological signs and showed striking progressive neurologic deterioration, especially cognitive decline and cerebellar dysfunction. Myoclonic involuntary movements and complete decapitated states followed in one or two months. The characteristic even pathognomonic in proper clinical settings, features of electroencephalography, magnetic resonance imaging and positron emission tomography and pathologic findings are presented.
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