J Korean Neuropsychiatr Assoc.
2009 Jul;48(4):207-212.
Neurobiology of Panic Disorder
- Affiliations
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- 1Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. bhyu@skku.edu
Abstract
- Panic disorder is a common mental disorder that causes considerable disability. However, the etiology of panic disorder remains unclear. Preclinical neuroanatomical and neurophysiological studies have provided clues to the neurobiological basis of panic disorder, and recent developments in neurobiological techniques in neurochemical research, brain imaging, and genetic research provide a further understanding of anxiety, fear, and panic disorder. In this article, we introduce a functional neuroanatomic model of fear and anxiety, and consider the implications of recent developments and debates in neurobiological findings with respect to panic disorder.