J Korean Neuropsychiatr Assoc.  2006 Jan;45(1):42-48.

Non-Relapse Rate in a 24 Week Follow-up Clinical Study with Korean Male Alcohol-Dependent Patients

• Kang CJ
• Kim SG
• Namkoong K
• Cho DH
• Lee BO
• Choi IG
• Choi YS
• Park SB
• Jae YM
• Kim HK
• Kim SY

Abstract

OBJECTIVES
In order to provide useful data for the further clinical studies with Korean alcohol-dependent patients, enrollment and non-relapse rates were investigated while alcohol-dependent patients were followed up for 24 weeks.
METHODS
The subjects of this study were alcohol-dependent male patients who, for the first time, visited a hospital among 3 groups of hospitals, University Hospital, General Hospital or Mental Hospital, or those who needed to be followed up after discharge from those hospitals. After assigning 12 subjects to each hospital, we investigated enrollment and non-relapse rates while cognitive-behavioral therapy and pharmacotherapy were provided.
RESULTS
1) Forty-eight patients were enrolled and the rate of enrollment was 36.4%. The enrollment rate in the University Hospital group was 52.1%, in the General Hospital group 50.0%, and in the Mental Hospital group 10.4%. 2) In 48 patients, non-relapse rate was 27.1% at 12 week and 18.8% at 24 weeks after starting follow-up. It was 24.4% and 20.0% at 12 and 24 weeks, repectively, in the University Hospital group while the General Hospital group showed 33.3% and 16.7%, respectively, and the Mental Hospital Group showed 20.0% at both 12 and 24 weeks.
CONCLUSION
These results provide important data for further clinical studies of Korean alcohol-dependent patients.

Keyword

Alcohol dependence; Clinical study; Non-relapse rate; Enrollment rate

MeSH Terms

Alcoholism
Drug Therapy
Follow-Up Studies*
Hospitals, General
Hospitals, Psychiatric
Hospitals, University
Humans
Male*