J Korean Neurosurg Soc.  2004 Mar;35(3):313-316.

Malignant Variant of the Central Neurocytoma

Affiliations
  • 1Department of Neurosurgery, College of Medicine, Dong-A University, Busan, Korea. kukim@mail.donga.ac.kr
  • 2Department of Pathology, College of Medicine, Dong-A University, Busan, Korea.

Abstract

Central neurocytoma is a rare, well-differentiated neuronal tumor and is usually located in the lateral or third ventricle of young adults. Its overall prognosis is excellent with a low proliferative index. The majority of previously reported malignant variants rarely did recurred after tumor removal and regarded as benign tumor despite of histopathological malignant feature. Nevertheless, we experienced a case of malignant variant of the central neurocytoma with high proliferative index(Ki-67 labeling index >30%), which showed recurrence immediately after surgery and died within 3 months POD. Here, we describe the case with a review of the literatures.

Keyword

Central neurocytoma; Recurrence; Ki-67 labeling index

MeSH Terms

Humans
Neurocytoma*
Neurons
Prognosis
Recurrence
Third Ventricle
Young Adult
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