J Korean Ophthalmol Soc.  2015 Jun;56(6):835-846. 10.3341/jkos.2015.56.6.835.

Risk Factors for Cataract Formation after Implantable Collamer Lens Implantation: Over a Mean 7.5-Year Follow-Up Period

• Lee D
• Seok JY
• Kyung HS
• Kim JM

• KMID: 2339147
• DOI: http://doi.org/10.3341/jkos.2015.56.6.835

Abstract

PURPOSE
To determine the risk factors and incidence of cataract formation over a long-term mean follow-up of 7.5 years after type V4 implantable collamer lens (ICL) implantation.
METHODS
We analyzed the preoperative, 3-month postoperative, 3-year postoperative, and last follow-up data of 228 eyes (118 patients) with mean preoperative spherical equivalent of -12.7 D and minimum postoperative follow-up of 3 years. Additionally, we determined the risk factors for cataract formation and calculated the 10.3 year cumulative cataract formation rate and 10.3 year cumulative cataract surgery rate using a survival curve.
RESULTS
After type V4 ICL implantation with minimum follow-up of 3 years, the calculated 10.3 year cumulative cataract formation rate was 20% and actual cataracts developed in 34 eyes (14.9%). The 10.3 year cumulative cataract surgery rate was 12% based on a survival curve and actual cataract surgery was performed in 12 eyes (5.3%). The risk factors for cataract formation were age (odds ratio [OR] = 1.10, p = 0.00), preoperative spherical equivalent (OR = 0.90, p = 0.00), crystalline lens thickness (OR = 9.54, p = 0.00), axial length (OR = 1.33, p = 0.00), 3 months postoperative vault (OR = 0.50, p = 0.03), and existence of peripheral touch between ICL optic margin and crystalline lens at last follow-up (OR = 7.84, p = 0.00).
CONCLUSIONS
We suggest one of the main risk factors for cataract formation after ICL implantation is decreased central vault and peripheral touch between ICL optic margin and crystalline lens.

Keyword

Cataract formation; ICL implantation; Peripheral touch; Risk factors

MeSH Terms

Cataract*
Follow-Up Studies*
Incidence
Lens, Crystalline
Risk Factors*

Figure

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  Figure 1. Superior or inferior peripheral crystalline lenticular touch by superior or inferior periphery of implantable collamer lens (ICL). (A) The arrows indicate the superior or inferior periphery of ICL is not touching the crystalline lens and there is no cataract formation. (B) It shows visually significant anterior subcapsular opacity. (C) The same eye with (B) shows the superior periphery of ICL is touching the crystalline lens (arrow).

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  Figure 2. Life table for cataract formation after implantable collamer lens (ICL) implantation. The moments when the initial cataract developed in group A or B patients after ICL implantation were regarded as “censored” in this survival curve.

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  Figure 3. Life table for cataract surgery after implantable collamer lens (ICL) implantation. The moments when the patients in group A underwent cataract surgery were regarded as “censored” in this survival curve.

Reference

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