J Korean Ophthalmol Soc.  2013 Dec;54(12):1832-1837.

The Usefulness of Fibrinogen-Thrombin Adhesives for Management of Conjunctival Closure in Scleral Buckling Operation

• Park KS
• Kim SW
• Woo JM

Abstract

PURPOSE
We investigated the efficacy of fibrin glue for conjunctival closure in scleral buckling operations.
METHODS
Thirty-seven eyes of 35 patients who underwent conjunctival closure for a scleral buckling operation with a minimum follow-up period of 3 months were evaluated. Postoperative discomfort (average score), presence of remnant adhesives, scleral buckle material infection, and wound dehiscence were evaluated prospectively in 35 eyes of 33 patients undergoing surgery with fibrin glue.
RESULTS
The eyes showed decreasing conjunctival injection and hemorrhage over time and near to full recovered without any treatment after 1 month. With time, the average discomfort score decreased significantly (p < 0.05) and wound dehiscence was found in only 1 eye. There was no adhesive remnant in any of the eyes.
CONCLUSIONS
The use of fibrin glue for conjunctival closure in scleral buckling operations is excellent as a cosmetic and functional method. The glue can reduce postoperative discomfort and is especially useful as a method to replace conventional conjunctival sutures.

Keyword

Conjunctival Closure; Fibrin Glue; Scleral Buckling Operation; Tissue Adhesives

MeSH Terms

Adhesives*
Fibrin Tissue Adhesive
Follow-Up Studies
Hemorrhage
Humans
Methods
Prospective Studies
Scleral Buckling*
Sutures
Tissue Adhesives
Wounds and Injuries
Adhesives
Fibrin Tissue Adhesive
Tissue Adhesives

Figure

• 

  Figure 1. Wound dehiscence (arrow) at the nasal side after scleral buckling using tissue adhesives. But adhesion was maintained between conjunctiva and sclera. Dehiscence size decreased as time passed and nearly recovered without any treatment after 1 month.

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  Figure 2. Series of photographs of a patient after scleral buckling using tissue adhesives. The eye showed decreasing conjunctival injection and hemorrhage as time passed and near full recovered without any treatment after 1 month.

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  Figure 3. Discomfort sign and symptoms (average score) in the patients after scleral buckling using tissue adhesives. As time passed, the average score decreased significantly (* p < 0.05, Wilcoxon's signed-ranks test).

Reference

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