J Korean Ophthalmol Soc.  2013 Aug;54(8):1298-1302.

Intravitreal Bevacizumab Injection in Diabetic Papillopathy

Affiliations
  • 1Department of Ophthalmology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. ckseek@schmc.ac.kr

Abstract

PURPOSE
To report a case where intravitreal bevacizumab injection was an effective treatment for diabetic papillopathy in a type 2 diabetic patient.
CASE SUMMARY
A 47-year-old male with a 10-year history of diabetes mellitus type 2 presented to our clinic for evaluation of diabetic retinopathy. There were no subjective symptoms including blurred vision or visual defect, and best corrected visual acuity (BCVA) was 20/20 in the right eye and 20/30 in the left eye. Fundus examination showed hyperemic optic disc swelling with telangiectatic new vessels, and fluorescein angiography leakage from the optic disc with neovascularization. The patient underwent fractionated panretinal photocoagulation. Ten days later, he complained of painless blurred vision with significant optic nerve head swelling and BCVA was 20/80 in the left eye. Intravitreal bevacizumab injection was administered, optic disc swelling was significantly decreased and BCVA improved to 20/30 after two months.
CONCLUSIONS
Diabetic papillopathy with severe decreased visual acuity can be treated with intravitreal bevacizumab injection.

Keyword

Bevacizumab injection; Diabetic papillopathy

MeSH Terms

Antibodies, Monoclonal, Humanized
Diabetes Mellitus
Diabetic Retinopathy
Eye
Fluorescein Angiography
Humans
Light Coagulation
Male
Optic Disk
Vision, Ocular
Visual Acuity
Bevacizumab
Antibodies, Monoclonal, Humanized

Figure

  • Figure 1. (A) Fundus photography showing the optic disc swelling in the left eye at patient’s first visit. (B) Early phase fluorescein angiography shows the optic-disc leakage due to neovascularization.

  • Figure 2. (A) At 10 days after initial presentation, fundus photography shows marked the optic disc swelling and hemorrhage in the left eye, with decreased visual acuity. (B) Fluorescein angiography shows hyperfluorescence on the optic disc early phase, (C) leakage from telangiectatic vessels, late phase. (D) After intravitreal bevacizumab injection, there is significantly reduced swelling of the optic disc. BCVA improved from 20/400 to 20/30.

  • Figure 3. (A) SD-OCT showed hyporeflective subfoveal space and macular edema, which continued as the optic disc swelling in the left eye at patient’s first visit. (B) Two months after treatment, hyporeflective subfoveal space and macular edema were resolved in the left eye.


Reference

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