J Korean Ophthalmol Soc.  2012 Oct;53(10):1528-1531.

Anterior Uveitis and Keratitis in Takayasu's Arteritis

• Seo HW
• Kim JH
• Lee DH
• Lee JH

Abstract

PURPOSE
To report a rare case of simultaneous uveitis and keratitis in Takayasu's arteritis.
CASE SUMMARY
A 22-year-old woman presented with complaints of redness and decrease in vision in both eyes. The patient was diagnosed a decade earlier as having Takayasu's arteritis. No other systemic or ophthalmic abnormalities were found. She complained of ophthalmic symptom aggravation during an upper respiratory infections and before menstruation. Bilateral corneal edema, conjunctival injection, and anterior uveitis were observed on slit-lamp examination. Concurrent treatments were started in consultation with an internist. Steroid eye drop and steroid systemic administration relieved the ocular pain and symptoms.
CONCLUSIONS
When a patient presents with recurrent red eyes and visual disturbances with Takayasu's ateritis, simultaneous uveitis and keratitis due to Takayasu's arteritis should be considered as a possible diagnosis.

Keyword

Anterior uveitis; Keratitis; Takayasu's arteritis

MeSH Terms

Corneal Edema
Eye
Female
Humans
Keratitis
Menstruation
Respiratory Tract Infections
Takayasu Arteritis
Uveitis
Uveitis, Anterior
Vision, Ocular
Young Adult

Figure

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  Figure 1 Twenty two years old female with Takayasu's disease, showing edematous cornea (A) and conjunctival injection (B)(Left eye).

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  Figure 2 Fundus photographs taken at the initial visit. The right eye (A) looks clean than the left eye (B) due to corneal edema and uveitis.

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  Figure 3 (A) Three-dimensional image of the heart and the aorta shows aneurysmal dilatation, proximal abdominal aorta. (B) Anterior part photograph shows clear cornea and conjunctiva (Left eye). (C) Fundus photograph taken at 2 weeks later. The image is much clear than 2 weeks ago.

Reference

1. Panja M, Mondal PC. Current status of aortoarteritis in India. J Assoc Physicians India. 2004. 52:48–52.

2. Chun YS, Park SJ, Park IK, et al. The clinical and ocular manifestations of Takayasu arteritis. Retina. 2001. 21:132–140.

3. Baba T, Itakura K, Tanaka R, et al. Importance of fluorescein angiographic study in evaluating early retinal changes in Takayasu disease. Jpn J Ophthalmol. 1999. 43:546–552.

4. Kiyosawa M, Baba T. Ophthalmological findings in patients with Takayasu disease. Int J Cardiol. 1998. 66:S141–S147.

5. Sagar S, Kar S, Gupta A, Sharma BK. Ocular changes in Takayasu's arteritis in India. Jpn J Ophthalmol. 1994. 38:97–102.

6. Peter J, David S, Danda D, et al. Ocular manifestations of Takayasu arteritis: a cross-sectional study. Retina. 2011. 31:1170–1178.

7. Kerr GS. Takayasu's arteritis. Rheum Dis Clin North Am. 1995. 21:1041–1058.

8. Kerr GS, Hallahan CW, Giordano J, et al. Takayasu arteritis. Ann Intern Med. 1994. 120:919–929.

9. Kaushik S, Gupta A, Gupta V, et al. Retinal arterial occlusion in Takayasu's arteritis. Indian J Ophthalmol. 2005. 53:194–196.

10. Kaliaperumal S, Gupta A, Sengupta S, Srinivasan R. Unilateral hemorrhagic keratouveitis as the initial presentation of Takayasu's arteritis. Indian J Ophthalmol. 2007. 55:397–398.

11. McDonald MA, Ojaimi E, Favilla I. Anterior uveitis in a child with Takayasu's arteritis. Clin Experiment Ophthalmol. 2004. 32:336–339.

12. Malhotra R, Gregory-Evans K. Management of ocular ischaemic syndrome. Br J Ophthalmol. 2000. 84:1428–1431.

13. Kim KC, Park JI, Lee J, et al. Clinical characteristics of Takayasu's arteritis. Korean Circ J. 2001. 31:1106–1116.

14. Direskeneli H, Aydin SZ, Merkel PA. Assessment of disease activity and progression in Takayasu\'s arteritis. Clin Exp Rheumatol. 2011. 29:S86–S91.