J Korean Ophthalmol Soc.  2012 May;53(5):681-688.

Amblyogenic Risk Factors in Primary Family Members of Patients with Exotropia

• Jang SY
• Choi YJ
• Kim SY
• Chang JH
• Park SH

Abstract

PURPOSE
To investigate the prevalence of amblyogenic risk factors in the primary family members (parents, siblings) of patients with exotropia.
METHODS
The authors of the present study examined primary family members including parents and siblings of 58 exotropia patients in our clinic. Best corrected visual acuity, refractive error, and cover-uncover test were performed. A total of 49 normal children's family members (control group) were examined in a similar manner. The prevalence of significant ocular findings were determined and compared to the control group.
RESULTS
In 58 eligible families (153 subjects except proband), 65.4% had significant ocular findings: In parents, anisometopia, astigmatism, hyperopia, and strabismus were found at a rate of 18.1%, 31.1%, 2.5%, and 11.2%, respectively. In siblings, anisometropia, astigmatism, hyperopia, and strabismus were found at a rate of 24.3%, 24.3%, 5.4%, and 18.9%, respectively. Compared to the control group, in parents of exotropia patients, anisometropia, astigmastim, and strabismus were observed at a higher rate. In siblings, anisometropia, and strabismus were observed at a higher rate.
CONCLUSIONS
Primary family members of exotropia patients have a high prevalence of amblyogenic risk factors. The present study offers rationale for providing comprehensive eye exams for parents and children with a family history of exotropia.

Keyword

Amblyogenic risk factor; Exotropia; Family history; Refractive error

MeSH Terms

Anisometropia
Astigmatism
Child
Exotropia
Eye
Humans
Hyperopia
Parents
Prevalence
Refractive Errors
Risk Factors
Siblings
Strabismus
Visual Acuity

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