J Korean Ophthalmol Soc.  2010 Mar;51(3):453-457.

A Case of Coats' Disease Accompanying A Retinal Macrocyst

Affiliations
  • 1Department of ophthalmology, Seoul National University College of Medicine, Seoul, Korea. ysyu@snu.ac.kr
  • 2Seoul Artificial Eye Center, Seoul National University, Clinical Research Institute, Seoul, Korea.

Abstract

PURPOSE
To report a case of laser photocoagulation treatment for the patient of Coats' disease accompanying a retinal macrocyst.
CASE SUMMARY
A three-year-old boy visited the hospital whose chief complaint was visual acuity decrease of his left eye. Fundus examination showed macular scar, foveal hard exudates and inferior retinal cystic lesion in his left eye. Two months later, examination under anesthesia (EUA) and fluorescein angiography (FAG) was performed. The results revealed inferior retinal macrocyst, nasal avascular retina and telangiectasia around the retinal macrocyst. Laser photocoagulation was performed around the retinal macrocyst and at the nasal avascular retina. One year after the laser photocoagulation, retinal macrocyst did not further progress and the retina was stabilized.
CONCLUSIONS
Laser photocoagulation was done around the retinal macrocyst and at the nasal avascular retina of the Coats' disease accompanying a retinal macrocyst and the lesions did not further progress and the retina was stabilized.

Keyword

Coats' disease; Laser photocoagulation; Retinal macrocyst

MeSH Terms

Anesthesia
Cicatrix
Exudates and Transudates
Eye
Fluorescein Angiography
Humans
Light Coagulation
Retina
Retinaldehyde
Telangiectasis
Visual Acuity
Retinaldehyde

Figure

  • Figure 1. Fundus photograph of the left eye taken on the day of the first visit. (A) Large retinal cystic lesion at the inferior to the inferotemporal major arcade is observed. (B) Foveal hard exudates and macular scar changes are also observed.

  • Figure 2. Ultrasonography of the left eye taken on the day of the first visit. Cystic lesion and intracystic hypoechoic signals are observed.

  • Figure 3. Fluorescein angiogram before the laser photocoagulation during the examination under anesthesia shows retinal macrocyst (A), telangiectatic vessel around the macrocyst and nasal avascular area (B).

  • Figure 4. Fundus photograph taken after the laser photocoagulation during the examination under anesthesia. Laser photocoagulation treatment was performed around the macrocyst (A) and at the nasal avascular area (B).

  • Figure 5. Fundus photograph taken one year after the laser photocoagulation. Retinal macrocyst (A) and nasal avascular area (B) are not progressed and stabilized.


Reference

References

1. Reese AB. Telangiectasis of the retina and Coats' disease. Am J Ophthalmol. 1956; 42:1–8.
Article
2. Choi SY, Yu YS. Treatment and clinical results of Coats' disease. J Korean Ophthalmol Soc. 1999; 40:2190–7.
3. Rubin MP, Mukai S. Coats' disease. Int ophthalmol clin. 2008; 48:149–58.
Article
4. Shields JA, Shields CL, Honavar SG, et al. Classification and management of Coats disease. The 2000 Proctor Lecture. Am J Ophthalmol. 2001; 131:572–83.
Article
5. Jones JH, Kroll AJ, Lou PL, Ryan EA. Coats' disease. Int Ophthalmol Clin. 2001; 41:189–98.
Article
6. Shields JA, Shields CL, Honavar S, Demirci H. Coats' disease. Clinical variations and complications of Coats' disease in 150 cases. The 2000 Sanford Gifford Memorial Lecture. Am J Ophthalmol. 2001; 131:561–71.
7. Imre G. Coats' disease. Am J Ophthalmol. 1962; 54:175.
8. Tolentino MJ, McLeod DS, Taomoto M, et al. Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate. Am J Ophthalmol. 2002; 133:373–85.
Article
9. Tolentino MJ, Miller JW, Gragoudas ES, et al. Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate. Ophthalmology. 1996; 103:1820–8.
Article
10. Su CY, Chen MT, Wu WS, Wu WC. Concentration of vascular endothelial growth factor in the subretinal fluid of retinal detachment. J Ocul Pharmacol Ther. 2000; 16:463–9.
Article
11. Sun Y, Jain A, Moshfeghi DM. Elevated vascular endothelial growth factor levels in Coats disease: rapid response to pegaptanib sodium. Graefes Arch Clin Exp Ophthalmol. 2007; 245:1387–8.
Article
12. Venkatesh P, Mandal S, Garg S. Management of Coats disease with bevacizumab in 2 patients. Can J Ophthalmol. 2008; 43:245–6.
Article
13. Alvarez-Rivera LG, Abraham-Marin ML, Flores-Orta HJ, et al. Coats' disease treated with bevacizumab. Arch Soc Esp Oftalmol. 2008; 83:329–31.
14. Couvillion SS, Margolis R, Mavrofjides E, et al. Laser treatment of Coats' disease. J Pediatr Ophthalmol Strabismus. 2005; 42:367–8.
Article
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