J Korean Ophthalmol Soc.  2017 Jul;58(7):870-874. 10.3341/jkos.2017.58.7.870.

Intravitreal Ranibizumab Injection in Adult-onset Coats' Disease: A Case Report

Affiliations
  • 1Department of Ophthalmology, Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea. sungpyo@hanafos.com

Abstract

PURPOSE
To report a case of adult-onset Coats' disease which showed decreased retinal edema and improved visual acuity following intravitreal ranibizumab injection.
CASE SUMMARY
A 21-year-old woman visited our hospital for decreased visual acuity in left eye from 3 months ago. Her best corrected visual acuity was 1.0 in the right eye, and 0.4 in the left eye. The intraocular pressure was 19 mmHg in the right eye and 16 mmHg in the left eye. At anterior segment examination, no abnormal findings were found. On fundus examination, subretinal exudates, superior retinal edema at posterior pole, and telangiectasia along superortemporal vascular arcade were observed in the left eye. Upon diagnosis as Coats' disease, intravitreal ranibizumab was performed, and laser photocoagulation was done around the retinal telangiectasia and nonperfusion area. Then, the second and third intravitreal ranibizumab injections were performed by a month, and her best visual acuity was improved to 0.8 and optical coherence tomography revealed decreased retinal edema.
CONCLUSIONS
We report a case of adult-onset Coats' disease. Intravitreal ranibizumab injection is effective in rapid visual improvement and decrease of retinal edema as combination therapy with laser photocoagulation which was a generalized treatment of choice in Coats' disease.

Keyword

Coats' disease; Intravitreal ranibizumab injection; Macular edema

MeSH Terms

Diagnosis
Exudates and Transudates
Female
Humans
Intraocular Pressure
Light Coagulation
Macular Edema
Papilledema
Ranibizumab*
Retinaldehyde
Telangiectasis
Tomography, Optical Coherence
Visual Acuity
Young Adult
Ranibizumab
Retinaldehyde
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