J Korean Ophthalmol Soc.  2004 Sep;45(9):1528-1534.

Clinical Findings and Prognosis of Persistent Hyperplastic Primary Vitreous

• Kyung HS
• Yu YS

Abstract

PURPOSE
To evaluate the clinical findings, visual improvement and preservation of eye according to treatment modality among children with persistent hyperplastic primary vitreous (PHPV) METHODS: A retrospective study, from 1982 to 2001, at Seoul National University Children's Hospital RESULTS: The subjects for investigation were 126 PHPV eyes in 114 children. The mean age at first exam was 3.6 +/- 3.5months, and the mean age at operation was 13.3 +/- 12.1months. Combined type (67%) was most common, followed by posterior (24%), and anterior (9%) types. The chief complaints in order of frequency were are leukocoria (35%), no fixation (23%), strabismus (21%), and microophthalmia (12%). Percentages of eye preservation and visual improvement over 20/1000 were 77%, and 57%, respectively. Nevertheless, the percentage of visual improvement over 20/200 in the anterior type was 25%. CONCLUSIONS: Combined type was most common in PHPV. Clinical findings and treatment modality varieds according to the type. Visual prognosis was poor. However, the post-treatment status was good in view of the treatment purpose. Therefore we can optain a good outcome through active treatment after the exact classification of PHPV eyes and by establishing the treatment purpose.

Keyword

Persistent hyperplastic primary vitreous (PHPV); Visual improvement

MeSH Terms

Child
Classification
Humans
Persistent Hyperplastic Primary Vitreous*
Prognosis*
Retrospective Studies
Seoul
Strabismus