J Korean Ophthalmol Soc.  2004 Sep;45(9):1427-1437.

Effect of the Spheric Multi-curve Lens on Changes of Corneal Topography and Endothelial Cell in Keratoconus

Affiliations
  • 1Department of Ophthalmology, Chungnam National University College of Medicine, Daejon, Korea. opht@unitel.co.kr
  • 2Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

PURPOSE
To analyze the effect of the spheric multi-curve lens on the changes of corneal topography and endothelial cells in keratoconic eye. METHODS: Forty-nine eyes of 37 keratoconic patients who had been followed more than 6 months were included in the study. Twenty-six eyes of 19 patients were fitted with spheric multi-curve lens, and the remaining 23 eyes of 18 patients were followed without any lens fitting as control. After spheric multi-curve lens fitting, visual acuity, and slit lamp examination were evaluated. Changes of corneal topography and endothelial cell were evaluated at first visit and 6 months after lens fitting. RESULTS: After lens fitting, 21 eyes (80.8%) showed best corrected visual acuity of better than 20/25. The value of the steepest Sim-K, shape factor (SF), and apical corneal power on corneal topography were significantly decreased in the spheric multi-curve lens fitting group compared to the control group (p<0.05). On the other hand, the value of the flattest Sim-K, and corneal irregularity measure (CIM) were not significantly changed (p>0.05). There were no significant differences in change of corneal endothelial cell density, mean cell area and percentage of hexagonal cell between the two groups (p>0.05). CONCLUSIONS: Short-term wearing of spheric multi-curve lens for 6 months in keratoconic patients showed no effect on progression of keratoconus and cornealendothelial cells.

Keyword

Corneal topography; Endothelial cell; Keratoconus; Spheric multi-curve lens

MeSH Terms

Corneal Topography*
Endothelial Cells*
Hand
Humans
Keratoconus*
Visual Acuity
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