J Korean Ophthalmol Soc.  1999 Jan;40(1):283-286.

Periodic Alternating Nystagmus Associated with Chiari-1 Malformation and Syringomyelia

Affiliations
  • 1The Institute of Vision Research, College of Medicine, Yonsei University.
  • 2Department of Ophthalmology, Yong-DongSeverance Hospita, Yonsei University College of Medicine.

Abstract

Periodic alternating nystagmus(PAN) is a form of spontaneous nystagmus with a specific pattern. It may be of congenital origin in many cases, and may be related to vestibulo-cerebellar system disease. It usually causes not only many ophthalmic problems such as decreased vision but also neurologic symptoms such as ataxic gait. So, ophthalmologist must perform both ophthalmic and neurologic examinations. Nystagmus can be treated with muscle relaxant. We report our experience about 30-year-old woman who complained of involuntary ocular movement and ataxic gait, and were diagnosed as PAN associated with Chiari-1 malformation and syringomyelia through electronystagmography and brain MRF.

Keyword

Chiari-1 malformation; Periodic alternating nystagmus; Syringomyelia

MeSH Terms

Adult
Brain
Electronystagmography
Female
Gait
Humans
Neurologic Examination
Neurologic Manifestations
Nystagmus, Pathologic*
Syringomyelia*
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