J Korean Ophthalmol Soc.  1996 Dec;37(12):2138-2143.

A Case of Candida Endophthalmitis

• Kim SK
• Lee EK

Abstract

Candida chorioretinitis is the most common fungal infection of the retina and choroid, and is one of the most common of all endogenous infections of the eye. The typical lesion of candida chorioretinitis is a white, circumscribed lesion, less than 1 mm in diameter, with an overlying haze of vitreous inflammatory cells. There may be vascular sheathing of retinal vessels in the area surrounding the lesions. Candida Endophthalmitia is defined as chorioretinitis with extension into vitreous or with intravitreal "puff balls". It has become an increasingly important cause of nosocomial infection, and has been documented in 9.9 % to 37% of adult patients with candidemia. We successfully treated one case of candida endophthalmitis with systemic administration of amphotericin B, itraconazole and intravitreal injection of amphotericin B in 18-year-old male after flame burn injury. We also performed pars plana vitrectomy with membrane peeling for the purpose of relieving preretinal traction membrane which had occurred after resolution of candida chorioretinitis.

Keyword

Amphotericin B; Candida Endophthalmitis; Itraconazole; Pars plana vitrectomy

MeSH Terms

Adolescent
Adult
Amphotericin B
Burns
Candida*
Candidemia
Chorioretinitis
Choroid
Cross Infection
Endophthalmitis*
Humans
Intravitreal Injections
Itraconazole
Male
Membranes
Retina
Retinal Vessels
Traction
Vitrectomy
Amphotericin B
Itraconazole