J Korean Ophthalmol Soc.
1990 Apr;31(4):469-475.
Results of Cyclotporin A therapy in Behcet's Disease
- Affiliations
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- 1Department of Ophthalmology, Yonsei University, College of Medicine, Seoul, Korea.
- 2Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
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15 patients with active Behcet's uveitis, suffering from marked deterioration of visual acuity in at least one eye were treated with cyclosporin A(CYA), 5 mg/kg/day for 6 months. All patients showed improved or same visual acuity after 1 month trial. All except 4 cases maintained same or improved visual acuity after trial of 6 months. There were minor side effects noted during the trial of 6 months except one who had suffered from the chronic persistent hepatitis. The authors conclude that CYA seems to be effective drug for the treatment of severe Behcet's uveitis.