J Korean Orthop Assoc.  2011 Oct;46(5):351-356.

Oncologic and Functional Outcomes of Extended Curettage for Low-Grade Central Chondrosarcoma

• Cho WH
• Lee SY
• Song WS
• Kong CB
• Cho SH
• Jeon DG

Abstract

PURPOSE
We analyzed the oncological and functional outcome of extended curettage for low-grade central chondrosarcoma.
MATERIALS AND METHODS
We retrospectively reviewed 16 patients with Grade I central chondrosarcomas treated with extended curettage and adjuvant therapy of chemical cauterization with H2O2 at a minimum follow up of 24 months.
RESULTS
Five-year disease free survival rate was 87.5%. Mean follow up was 82.7 months and no patient developed metastases or died of disease. The mean final Musculoskeletal Tumor Society functional score was 27.5 (91.6%).
CONCLUSION
Extended curettage is an effective treatment strategy for low-grade central chondrosarcoma with improved functional outcomes and lower complication rates compared to wide resection and reconstruction.

Keyword

central chondrosarcoma; low-grade; curettage

MeSH Terms

Chondrosarcoma
Curettage
Disease-Free Survival
Follow-Up Studies
Humans
Neoplasm Metastasis
Retrospective Studies

Figure

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  Figure 1 (A) Plain radiograph of a 52-year-old woman (Case 1) shows centrally located faint radiolucent and calcified lesion in distal metaphysis. (B) She was treated with curettage and bone cementation. (C) Histology of case 1 shows low cellularity and chondroid matrix (H&E, ×200). (D) After 7 months, pathologic fracture developed. (E) Open reduction & internal fixation was performed.

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  Figure 2 (A) Initial plain radiograph of a 51-year-old man (Case 8) shows mixed osteolytic and sclerotic lesion with calcifications in distal epi-metaphysis of right femur. (B) Histology of case 8 shows low cellularity and chondroid matrix (H&E, ×200). (C, D, E) He was treated with curettage and bone cementation, and after 14 months, local recurrence developed. (F) Re-curettage and bone cementation with ender-nail was performed.

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