J Korean Pediatr Soc.
1998 Nov;41(11):1601-1605.
A Case of Myositis Ossificans Progressiva
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea.
Abstract
- Myositis ossificans progressiva (MOP) is a rare, slow progressive autosomal dominant disorder that principally affects children under the age 10 years. It is characterized by progressive fibroblastic proliferation, and subsequent calcification and ossification of subcutaneous fat, muscles, tendons, aponeuroses and ligaments. The disorder is often associated with symmetrical malformations of the digits, especially microdactyly or adactyly of the thumbs and great toes. The disease usually leads to extensive immobility and eventual disability. We experienced a case of MOP in a 2-year-old male child who showed multiple tender nodules on the left occipital, superior and inferior scapular, mid-back and upper buttock area and digital malformations and was treated with etidronate disodium. A brief review of related literatures is also presented.
