J Korean Pediatr Soc.  1977 Dec;20(12):959-964.

Comparison of Tuberculine Testing Between Monotest and Mantoux

• Son BK

Abstract

The Monotest was compared with the Mantoux test. A total of 527 first grade primary school children were subjected to test. Each child was innoculated simultaneously to one side arm with protein purified derivatve(PPD, 1TU) and to the another side arm with Monovac(Institute Merieux). Results from each test were read seperately 72 hours after administration. When induration of 2mm or greater was considered a positive Monotest reaction and compared to a positive Mantoux reaction of 10mm or greater, the sensitivity of Monotest to mantoux test was 96.19% and the specificity was 88.39%. When induration of 5mm or greater was considered a positive Monotest reaction and compared to a positive Mantoux reaction of 10mm or greater, the sensitivity of Monotesto to to Mantoux test was 81.90% and the specificity was 96.68%. From this results I would assume that the Monovac test can be substituted for Mantoux test(PPd, 1TU), preferably 2mm or greater swelling of Monovacc test is considered as a positive result.

MeSH Terms

Arm
Child
Humans
Sensitivity and Specificity
Tuberculin*
Tuberculin