J Korean Sleep Res Soc.  2013 Jun;10(1):31-33.

A Case of Hypnic Headache Responded to Indomethacin

Affiliations
  • 1Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea. sleep.cho@gmail.com

Abstract

Hypnic headache (HH) is a primary headache disorder occurring exclusively during sleep in the elderly. Although pathophysiology of HH is still unknown, the association with chronobiological perspective and rapid eye movement sleep has been suggested. Lithium has been reported to be the most effective drug for HH. However, its usage may be limited because of its toxicity. Indomethacin could be alternative treatment option, which has better safety profile. We report a case of HH, which was successfully treated with indomethacin.

Keyword

Sleep; Hypnic headache; Indomethacin

MeSH Terms

Aged
Headache Disorders, Primary*
Humans
Indomethacin*
Lithium
Sleep, REM
Indomethacin
Lithium
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