J Korean Soc Coloproctol.  2001 Oct;17(5):277-282.

Natural Killer (NK) Cell Lymphoma of the Cecum with Perforation:A case of report

Affiliations
  • 1Department of Surgery, Wonju College of Medicine, Yonsei University, Wonju, Korea. iykim@wonju.yousei.ac.kr
  • 2Department of Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea.

Abstract

Natural Killer cell lymphoma pursued a highly aggressive clinical course, with the aggressiveness and poor prognosis in this biologically distinct primary gastrointestinal lymphoma, a more vigorous systemic therapy should be considered in the addition to surgery. We report an unusual case of aggressive primary Natural Killer cell (NK cell) lymphoma of the cecum. A 38-year old man admitted for intractable fever, diarrhea, and hematochezia. The patient diagnosed as primary NK cell cecal lymphoma with perforation after surgical resection. The primary lesion was deep ulceration with perforation and it revealed metastasis to liver. The immunophenotype of the tumor cell were CD56+, CD3+, UCHL-1+, CD45RO+, polyclonal IGH, TCRr, so confirmed NK cell type lymphoma.

Keyword

Natural Killer cell lymphoma; Cecum perforation; Poor prognosis

MeSH Terms

Adult
Cecum*
Diarrhea
Fever
Gastrointestinal Hemorrhage
Humans
Killer Cells, Natural
Liver
Lymphoma*
Neoplasm Metastasis
Prognosis
Ulcer
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