J Korean Epilepsy Soc.  2001 Dec;5(2):186-191.

A Case of Recurrent Dysembryoplastic Neuroepithelial Tumor in the Temporal Lobe

Affiliations
  • 1Department of Neurological Surgery, Asan Medical Center, College oc Medicine, University of Ulasn, Seoul, Korea. jklee@www.amc.seoul.kr
  • 2Department of Pediatric Neurology, Asan Medical Center, College oc Medicine, University of Ulasn, Seoul, Korea.
  • 3Department of Pathology, Asan Medical Center, College oc Medicine, University of Ulasn, Seoul, Korea.

Abstract

A boy since 6 years of his age who have had complex partial seizure was referred to our Department in March 1998. The left anterior temporal lobectomy with the resection of the head and body of hippocampus and gross total tumor removal was also performed in April 1998. He has been seizure free and stable about 3 years postoperatively. In January 2001, he revisited us due to headache, nausea, and vomiting from one week before. MRI revealed recurrence of the tumor, and a partial removal of the tumor was performed. Nine months from the second operation, the tumor recurred again and the thrid operation was followed. The pathologic findings were dysembryoplastic neuroepithelial tumor (DNT) in all three cases and no evidences of anaplastic changes were found in two recurrent cases. In general, DNT is known to be a disease that rarely transforms into the malignant, postoperative adjuvant radio-or chemotherapy is unnecessary even after partial resection of the tumor. However, in our case, there were two episodes of recurrence after the total resection. Here, we report the first case of recurrent DNT even after the total resection within three years in our knowledge.

Keyword

Dysembryoplastic neuroepithelial tumor (DNT); Recurrence; Anaplastic change
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