J Korean Child Neurol Soc.
2013 Mar;21(1):33-37.
A Case of Developmental Regression with Hypsarrhythmia on EEG Treated with Pulse Methylprednisolone
- Affiliations
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- 1Department of pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea. sjyou@paik.ac.kr
Abstract
- Infantile spasms (IS) is a type of epileptic encephalopathy with poor developmental outcomes. The goal of treatment is complete control of spasms, improvement of hypsarrhythmia, and rapid reversal of delayed development. Improvements in diagnosis can result in the selection of appropriate therapy, which can improve a patient's developmental outcomes. However, there is no consensus on the best initial treatment for IS. Here, we describe 6-month-old boy with severe periventricular leukomalacia, developmental regression, and hypsarrhythmic pattern on electroencephalography, who was successfully treated with intravenous methylprednisolone.
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