J Korean Burn Soc.  2014 Jun;17(1):25-29.

Effect of Plant Extracts Contained Dressing Material Which Is Rich in Procyanidins for Treatment of Deep Second Degree Burn

• Lee YJ
• Yoon J
• Yang HT
• Cho YS
• Kym D
• Kim JH
• Hur J
• Chun W
• Yim H

Abstract

PURPOSE
This study was planned to evaluate the effect of plant extracts contained dressing material which is rich in procyanidins for treatment of deep second degree burn.
METHODS
This study conducted from September 1, 2013 to February 28, 2014. Patients with the deep dermal burn wound which is larger than 200 cm2 were enrolled in this study. The test material was applied total 3 times every 2 days when the wounds were relatively clean, with thin eschar and scab removed and the dermal layer exposed. The test and control sites were treated with hydro-foam equally. The effectiveness was evaluated by comparing the re-epithelialization rates between the test and control sites. Two burn surgeons blindly evaluated for re-epithelialization. Evaluation of adverse reaction was also performed during study period.
RESULTS
Total of 40 patients were enrolled. Mean total body surface area burned% was 12.3+/-5.5% and the test material was first applied at mean post burn day # 7.2+/-2.0.The re-epithelialization period was 9.0+/-1.7 days in the test site and 11.1+/-2.0 days in the control site. In the test site, re-epithelialization was 2.1+/-1.0 days faster than in the control site (P<0.0001). There was no significant adverse reaction during study period.
CONCLUSION
The plant extracts contained dressing material which is rich in procyanidins accelerates wound healing time and shows the safety.

Keyword

Deep second degree burn; Procyanidin

MeSH Terms

Bandages*
Body Surface Area
Burns*
Humans
Plant Extracts*
Proanthocyanidins*
Re-Epithelialization
Wound Healing
Wounds and Injuries
Plant Extracts
Proanthocyanidins