J Korean Androl Soc.
1993 Dec;11(2):121-124.
Effect Of Alpha: Adrenergic Blocker In Thermoresistant Benign Prostatic Hyperplasia
- Affiliations
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- 1Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- After thermotherapy in 100 patients with benign prostatic hyperplasia(BPH), the overall improvement rate-defined as more than 50% subjective or objective improvement-was 64%, but both subjective and objective symptom improvement were seen in only 26%. We evaluated the effectiveness of an alpha-adrenergic blocker in the 57 patients with thermoresistant BPH(i.e., those who did not have a complete response), beginning at least 1 month after thermotherapy. After at least 1 month of treatment, the overall improvement rate was 47%(27/50). Therefore, the combined improvement rate of thermotherapy plus an alpha-adrenergic blocker in the 83 patients available for follow-up was 87%. We conclude that the use of an alpha-adrenergic blocker in patients with thermoresistant BPH increases their chance of avoiding operation.