J Neurogastroenterol Motil.  2011 Apr;17(2):164-168.

The Value of Carlsson-Dent Questionnaire in Diagnosis of Gastroesophageal Reflux Disease in Area With Low Prevalence of Gastroesophageal Reflux Disease

• Netinatsunton N
• Attasaranya S
• Ovartlarnporn B
• Sangnil S
• Boonviriya S
• Piratvisuth T

Abstract

BACKGROUND/AIMS
Symptom-based diagnosis for gastroesophageal reflux disease (GERD) has been accepted in the population with high prevalence. Carlsson-Dent questionnaire (CDQ) is a standardized symptom-based diagnosis tool for GERD. The value of this tool in the population with low prevalence is unknown. The aim of this study was to determine CDQ performance for diagnosis of GERD in Thai population with low prevalence versus endoscopy or 24 hour pH monitoring.
METHODS
Patients with dyspepsia by Rome II criteria were recruited. All patients completed a Thai version of CDQ and underwent endoscopic examination. Those without esophagitis or peptic ulcer and positive CDQ score took pH monitoring.
RESULTS
One hundred patients (68 female) with mean age +/- SD of 45.6 +/- 12.4 years were recruited. Six with Los Angeles grade A esophagitis had negative CDQ score. In 44 with positive CDQ score, 3 had Los Angeles grade B esophagitis and 41 had pH monitoring done with 8 having positive test. The GERD diagnosis by CDQ was confirmed in 11 of 44 patients (25%). CDQ detected 11 out of 17 GERD detected by endoscopy and pH monitoring and the sensitivity of CDQ was 64%.
CONCLUSIONS
CDQ diagnosed more GERD in Thai population with low prevalence compared with endoscopy and pH monitoring. This may be due to some patients with functional heartburn were picked up by CDQ and some patients with GERD were not detected by endoscopy and pH monitoring.

Keyword

Diagnosis; Gastroesophageal Reflux; Questionnaires

MeSH Terms

Asian Continental Ancestry Group
Dyspepsia
Endoscopy
Esophagitis
Gastroesophageal Reflux
Heartburn
Humans
Hydrogen-Ion Concentration
Los Angeles
Peptic Ulcer
Prevalence
Surveys and Questionnaires
Rome