J Korean Acad Rehabil Med.
2007 Aug;31(4):482-485.
Cervical Osteomyelitis and Radiculopathy due to Candida: A case report
- Affiliations
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- 1Department of Rehabilitation Medicine, Soonchunhyang University College of Medicine, Korea. redhot911@hanmail.net
- 2Department of Pathology, Soonchunhyang University College of Medicine, Korea.
Abstract
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Candida species inhabit the skin and mucous membranes of healthy individuals with low virulence, and osteomyelitis due to Candida is very rare. However, incidence of invasive candidal infection is increasing by intravenous drug use, broad spectrum antibiotics, and indwelling central venous catheter. A 63 year old man with cervical pain radiating to left scapula and upper extremity, who had undergone an appendectomy followed by broad spectrum intravenous antibiotics therapy for 3 weeks, visited outpatient clinic. The results of electrophysiologic study was compatible with left C6 and C7 radiculopathy, and cervical MRI and bone scan findings were suggestive of osteomyelitis. Pathologic findings of tissue biopsy showed bone destruction with acute and chronic nonspecific inflammation, and tissue culture and staining revealed Candida famata.