J Korean Soc Transplant.
2008 Dec;22(2):197-202.
Steroid Withdrawal in Renal Transplantation
- Affiliations
-
- 1Department of Internal Medicine, BongSeng Hospital, Busan, Korea. kidney119@hotmail.com
Abstract
- Steroid is a critical component of immunosuppressive regimen. Unfortunately, steroid is associated with numerous adverse effects including diabetes, hypertension, hyperlipidemia, osteoporosis, sodium retention, and avascular necrosis. These adverse effects have prompted trials of steroid withdrawal with introduction of potent immunosuppressive agents in renal transplantation. Although late steroid withdrawal raised acute rejection rate compared with early steroid withdrawal, results of recent trials that used diverse steroid withdrawal protocols suggest good short and long term graft outcomes. But, in patients survival, patients with steroid withdrawal is similar to patients administered steroid. This review summarizes usefulness according to timing of steroid withdrawal and re-exams benefits of steroid withdrawal in renal transplantation.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Prospective Controlled Protocol for Three Months Steroid Withdrawal with Tacrolimus, Basiliximab, and Mycophenolate Mofetil in Renal Transplant Recipients
- A case of successful late steroid withdrawal after ABO-incompatible kidney transplantation
- Safety and Efficacy of Early Steroid Withdrawal with Thymoglobuline Induction in Kidney Transplantation
- The Effect of Steroid and other Immunosuppressants on the Cataract and after-Cataract after Renal Transplantation
- Safety and metabolic advantages of steroid withdrawal after 6-months post-transplant in de novo kidney transplantation: 1-year prospective cohort study
