J Korean Acad Rehabil Med.  2003 Jun;27(3):349-354.

Deep Venous Thrombosis and Heterotopic Ossification in the Patients with Traumatic Spinal Cord Injury

• Rah UW
• Kim HS
• Moon HW
• Lee IY
• Eom JH
• Lee JB

Abstract

OBJECTIVE
To investigate the incidence, time of onset, and risk factors of deep vein thrombosis asssociated with heterotopic ossification in patients with spinal cord injury. METHOD: The medical records of 201 patients with spinal cord injury were reviewed. Duplex ultrasound and/or venography were used for the diagnosis of deep vein thrombosis and 3 phase bone scan and/or plain radiologic studies were used for the diagnosis of heterotopic ossification. RESULTS: Whereas the incidence of heterotopic ossification and deep vein thrombosis in this population were 10.0% and 4.5%, respectively, 55.5% of the individuals with deep vein thrombosis developed heterotopic ossification. The overall incidence of coexistence of deep vein thrombosis and heterotopic ossification was 2.5%. The significant difference between the occurrence of heterotopic ossification and deep vein thrombosis in this SCI population reached statistical significance (Fisher's exact test p<0.005). CONCLUSION: The results of this study suggest that there exists an association between the occurrence of deep vein thrombosis and heterotopic ossification following SCI.

Keyword

Heterotopic ossification; Deep venous thrombosis; Spinal cord injury

MeSH Terms

Diagnosis
Humans
Incidence
Medical Records
Ossification, Heterotopic*
Phlebography
Risk Factors
Spinal Cord Injuries*
Spinal Cord*
Ultrasonography
Venous Thrombosis*