Changes of the Platelet Parameters in Cerebral Infarction

Cho, Sung Chan; Chun, Min Ho; Ha, Sang Bae

Abstract

The purpose of this study is to evaluate any significant changes of the platelet parameters in pre-stroke stage and post-stroke stage compared with those of control group, and to determine any correlation of the platelet parameters with outcome of stroke patients as well as cerebral lesion size. We reviewed 53 charts of stroke patients who were admitted to neurology service first and then rehabilitation unit of Asan Medical Center. The results of study revealed that there were no significant changes in mean platelet volume and platelet counts of stroke patients in pre-stroke stage, acute stage (<48 hours after stroke) and chronic stage (>4 months) as compared with those of control group. Furthermore, there were no significant changes of platelet parameters between survived group and expired group in pre-stroke stage and post-stroke stage. This study showed no correlation between the size of cerebral lesion and the platelet parameters. The review of FIM(functional independence measure) scores of sampled patients failed to demonstrate any functional correlations with platelet parameters. In cerebral infarct patients, there were no significant differences of platelet parameters between each groups. There was also no significant correlation between the size of cerebral lesion, functoinal outcomes and platelet parameters. However, future study on prognostic values of platelet parameters in cerebral infarct patients needs to be carried out.