J Korean Acad Oral Health.  2014 Dec;38(4):232-237. 10.11149/jkaoh.2014.38.4.232.

Relation between rheumatoid arthritis and periodontal diseases: Using the Fifth Korea National Health and Nutrition Examination Survey

Affiliations
  • 1Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea. kbsong@knu.ac.kr
  • 2Department of Dental Hygiene, Ulsan College, Ulsan, Korea.
  • 3Department of Dental Hygiene, College of Science & Technology, Kyungpook National University, Sangju, Korea.

Abstract


OBJECTIVES
Rheumatoid arthritis (RA) has been associated with systemic diseases, such as periodontal diseases. Periodontal diseases and RA appear to share many pathologic features. The etiology of the two diseases may differ, but they share similar pathological characteristics. Therefore, the aim of this study was to evaluate the correlation between RA and periodontal diseases.
METHODS
Data from the Fifth Korea National Health and Nutrition Examination Survey (KNHNES) were used to analyze periodontal status according to the presence of RA. Demographics and oral behaviors were analyzed using the complex chi-square test to compare participants with RA with those without RA. Complex logistic regression was used to analyze relationships of periodontal diseases with RA and other covariates.
RESULTS
The odds ratio for periodontal diseases was 1.91 (95% confidence interval: 1.05-3.48) in participants with RA compared with participants without RA.
CONCLUSIONS
The results of this study provide evidence of a significant association between periodontal diseases and RA.

Keyword

Korea National Health and Nutrition Examination Survey (KNHNES); Periodontal diseases; Rheumatoid arthritis (RA)

MeSH Terms

Arthritis, Rheumatoid*
Demography
Korea
Logistic Models
Nutrition Surveys*
Odds Ratio
Periodontal Diseases*

Figure

  • Fig. 1. Flow chart.


Reference

References

1. Moon HS. Suggestions for professionalization and improvement of oral health ministration in Korea. J Korean Dent Assoc. 1997; 6:351–352.
2. Burt B. Position paper: Epidemiology of periodontal diseases. J Periodontol. 2005; 76:1406–1419.
3. Ji JD, Lee YH, Song GG. Prostaglandin E2 (PGE2): Roles in immune responses and inflammation. J Rheum Dis. 2004; 11:307–316.
4. Arnett F, Edworthy S, Bloch DA, Mc Shane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis and Rheumatism. 1988; 31:315–324.
Article
5. Harris ED, Kelly WN, Sledge CB. Clinical features of rheumatoid arthritis. Textbook of rheumatology. 5th ed.Philadelphia: WB Saunders;1997. p. 898.
Article
6. Ji JD, Kim TH, Lee B, Choi SJ, Lee YH, Song GG. Expression of osteoclastogenesis- related genes in rheumatoid arthritis synovial macrophages. J Rheum Dis. 2011; 18:11–18.
7. Lee L, Manolisos N. Therapeutic horizons for rheumatoid arthritis. Today's Life Science. 1999; 11:42–48.
8. Silman AJ. Commentary: do genes or environment influence development of rheumatoid arthritis? Br Med J. 2002; 324:264.
9. Yavuzyilmaz E, Yamalik N, Calguner M, Ersoy F, Baykara M, Ye-niay I. Clinical and immunological characteristicsof patients with rheumatoid arthritis and periodontal disease. J Nih on Univ Sch Dent. 1992; 34:89–95.
10. Sjostrom L, Laurell L, Hugoson A. Hakansson J. Periodontal conditions in adults with rheumatoid arthritis. Comm Dent Oral Epidemiol. 1989; 17:234–236.
11. Kasser UR, Gleissner C, Dehne F, et al. Risk for periodontal disease in patients with longstanding rheumatoid arthritis. Arth ritis Rheum. 1997; 40:2248–2251.
12. Albandar JM. Some predictors of radiographic alveolar bone height reduction over 6 years. J Periodont Res. 1990; 25:186–192.
Article
13. Pischon N, Pischon T, Kroger J, Gulmes E, Kleber BM, Berni-moulin JP, et al. Association among rheumatoid arthritis, oral hygiene, and periodontitis. J Periodontol. 2008; 79:979–986.
Article
14. Williams RC, Offenbacher S. Periodontal medicine: the emergence of a new branch of periodontology. Periodontol 2000. 2000; 23:9–12.
Article
15. Eversole JL. Systemic humoral immune response in periodontal disease. Crit Rev Oral Biol Med. 1990; 1:283–331.
16. Ministry of Health and Welfare. 2012 Korean National Health and Nutrition Examination Survey. Seoul: Ministry of Health and Welfare;2012. p. 3–21.
17. Pischon N, Heng N, Bernimoulin JP, Kleber B, Willich S, Pischon T. Obesity, inflammation, and periodontal disease. J Dent Res. 2007; 86:400–409.
Article
18. Albandar JM. Epidemiology and risk factors of periodontal diseases. Dent Clin North Am. 2005; 49:517–532.
Article
19. Merchant AT, Pitiphat W, Franz M, Joshipura K. Whole-grain and fiber intakes and periodontitis risk in men. Am J Clin Nutr. 2006; 83:1395–1400.
Article
20. Elliot D, Robert A, Greenwald Laura J, Kushner Gerald W. Hypothesis: The humoral immune response to oral bacteria provides a stimulus for the development of rheumatoid arthritis. Inflammation. 2004; 6:311–318.
Article
21. Ribeiro J, Leao A, Novaes AB. Periodontal infection as a possible.
22. Mercado FB, Marshall RI, Bartold PM. Inter-relationships between rheumatoid arthritis and periodontal disease. J Clin Peri-odontol 2003;30:761-772. severity factor for rheumatoid arthritis. J Clin Periodontol. 2005; 32:412–416.
23. Snyderman R, McCarty GA. Analogous mechanism of tissue destruction in rheumatoid arthritis and periodontal disease. Genco RJ, Mergenhagen SE, editors. Host parasite interactions in periodontal diseases. Washington DC: American Society for Mi-crobiology;1982. p. 354–362.
24. De Pablo F, Chapple ILC, Christopher D, Buckley CD, Thomas D. Periodontitis in systemic rheumatic diseases. Rheumatology. 2009; 5:218–224.
Article
25. Mercado F, Marshall RI, Klestov AC, Bartold PM. Is there a relationship between rheumatoid arthritis and periodontal disease? J Clin Periodontol. 2000; 27:267–272.
Article
26. De Pablo F, Dietrich T, McAlindon TE. Association of periodontal disease and tooth loss with rheumatoid arthritis in the US population. J Rheumatol. 2008; 35:70–76.
27. Eduardo PI, Manoel BB, Carlos R, Keith LK, Mirian AO. Peri- odontal condition in patients with rheumatoid arthritis. Brax Oral Res. 2008; 22:72–77.
28. Dissick A, Redman RS, Jones M, Rangan BV, Reimold A, Griffiths GR, et al. Association of periodontitis with rheumatoid arthritis: a pilot study. J Periodontol. 2010; 81:223–230.
Article
29. Kasser UR, Gleissner C, Dehne F, Michel A, Willershausen-Zonnchen B, Bollten WW. Risk for periodontal diseases in patients with longstanding rheumatoid arthritis. Arthritis Rheum. 1997; 40:2248–2251.
30. Nasse W, Dijkstra PU, Abbas F, Spijkervet FKL, Stijger A, Tromp JAH, et al. Increased prevalence of cardiovascular and autoimmune diseases in periodontitis patients: a cross-sectional study. J Periodontol. 2010; 81:1622–1628.
31. Tolo K, Jorkjend L. Serum antibodies and loss of periodontal bone in patients with rheumatoid arthritis. J Clin Periodontol. 1990; 17:288–291.
Article
Full Text Links
  • JKAOH
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr