World J Mens Health.  2012 Aug;30(2):123-130.

Strong Impact of Nocturia on Sleep Quality in Patients with Lower Urinary Tract Symptoms

• Doo SW
• Lee HJ
• Ahn J
• Kim JH
• Yun JH
• Yang WJ
• Song YS

Abstract

PURPOSE
Nocturia is a bothersome symptom that impacts sleep quality in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH). This study was performed to evaluate the impact of nocturia on sleep quality.
MATERIALS AND METHODS
A total of 58 male patients with LUTS/BPH were enrolled. LUTS/BPH patients without nocturia were included in the control group. The inclusion criteria were eight or more points on the International Prostate System Score (IPSS) including more than one episode of nocturia and a prostate volume larger than 20 ml. IPSS, prostate volume, uroflowmetry, and the Pittsburgh Sleep Quality Index (PSQI) from each patient were recorded.
RESULTS
Patients with nocturia showed a higher mean global PSQI (8.5+/-0.4) than patients without nocturia (4.82+/-0.4) (p<0.01). Patients with nocturia showed a higher percentage of severe sleep disorders (74.1%) than patients without nocturia (35.3%) (p<0.01). The regression coefficient between the number of episodes of nocturia and mean global PSQI was 0.42 (p<0.01).
CONCLUSIONS
Patients with nocturia showed poor sleep quality, and this was related to the number of episodes of nocturia. This suggests that nocturia has a strong impact on sleep quality in patients with LUTS/BPH.

Keyword

Nocturia; Sleep; Prostatic hyperplasia

MeSH Terms

Humans
Lower Urinary Tract Symptoms
Male
Nocturia
Prostate
Prostatic Hyperplasia
Sleep Wake Disorders

Figure

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  Fig. 1 Mean global PSQI of the patients without and with nocturia. Nocturia has an impact on patient's sleep (p<0.01, ANOVA test). PSQI: Pittsburgh Sleep Quality Index.

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  Fig. 2 Severe sleep disorders of the patients without and with nocturia. Nocturia has an impact on patient's sleep (p<0.01, chi-square test). A total Pittsburgh Sleep Quality Index over 5 is considered an indicator of severe sleep disorders.

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  Fig. 3 Regression coefficiency of number of nocturia and global PSQI score. R=0.42 (p<0.01, Pearson correlation test). PSQI: Pittsburgh Sleep Quality Index, R: regression coefficient.

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