Tuberc Respir Dis.  2014 Jul;77(1):24-27.

Takotsubo Cardiomyopathy Caused by Pulmonary Tuberculosis: A Case Report

Affiliations
  • 1Division of Pulmonology, Critical Care and Sleep Medicine, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. mdlee@gmail.com

Abstract

Takotsubo cardiomyopathy (TTC) is defined as a reversible, acute ventricular dysfunction without any evidence of coronary artery obstruction. There have been reports of TTC caused by emotional or physical stress, drug use, hormone imbalance, or medical conditions such as pulmonary disease, sepsis, and trauma, but a relationship between TTC and pulmonary tuberculosis has not previously been reported. From our knowledge, this is the first report of TTC caused by pulmonary tuberculosis.

Keyword

Takotsubo Cardiomyopathy; Tuberculosis, Pulmonary; Catecholamines

MeSH Terms

Catecholamines
Coronary Vessels
Lung Diseases
Sepsis
Takotsubo Cardiomyopathy*
Tuberculosis, Pulmonary*
Ventricular Dysfunction
Catecholamines

Figure

  • Figure 1 (A) Initial chest radiograph shows numerous nodules in both apices suggesting active pulmonary tuberculosis. (B) Chest computed tomography (CT) shows cavitary lesions in the right upper lobe and multiple small nodules and patchy consolidation in both upper lobes. (C) Chest CT shows an approximately 1.9-cm ovoid filling defect (arrow) in the apex of the left ventricle.

  • Figure 2 Transthoracic echocardiography. (A) The typical apical ballooning of Takotsubo cardiomyopathy in the initial apical four-chamber view. (B) The 1.6×1.2-cm thrombus in the apex of the left ventricle is noted in the initial apical two-chamber view. (C) In a follow-up of echocardiography, apical ballooning is completely normalized. (D) On follow-up echocardiography, the thrombus was still noted, but decreased in size. Arrows indicate the apical thrombus.


Reference

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