Yeungnam Univ J Med.
1998 Dec;15(2):359-370.
A Clinicopathologic Review of Eight Cases of Chondroblastoma
- Affiliations
-
- 1Department of Pathology, College of Medicine, Yeungnam University, Taegu, Korea.
- 2Department of Orthopedic Surgery, College of Medicine, Yeungnam University, Taegu, Korea.
- 3Department of Diagnostic Radiology College of Medicine, Yeungnam University, Taegu, Korea.
Abstract
- Eight cases of chondroblastoma were studied by analyzing the clinical and pathologic findings. The age of eight cases ranged from 17 to 38 years old(median age, 22.7 years old). The tumors developed in the femur (3 cases), patella (2 cases), tibia( 1 case), fibula (1 case), and ulna (1 case). The mean diameter of tumors was 4.0 cm (range, 1.5 to 8.0 cm). Grossly, tumors showed grayish brown solid area with foci of secondary aneurysmal bone cyst. Histologically, the tumor cells were round or polygonal in shape with nuclear groove. And there were chondroid differentiation(7 cases), mitosis(3 cases), calcific deposits(3 cases), secondary aneurysmal bone cyst(4 cases), hemosiderin deposits(4 cases), necrosis(3 cases), vascular invasion(1 caes) and foamy histiocytes and cholesterol cleft(1 cases). All cases showed no metastasis to lymph node and distant organ. Seven cases (87.5 %) were immunoreactive for S-100 protein. None were immunoreactive for cytokeratin.
