Endobronchial Metastasis of Epithelioid Sarcoma
- Affiliations
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- 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine, Seoul, Korea. ywkim@snu.ac.kr
Abstract
- Epithelioid sarcomas are rare soft tissue sarcomas with a high tumor grade and high local recurrence and metastasis rates. Although the lung is the most common site of metastasis, endobronchial metastasis hasn't been reported yet. We now report a case of epithelioid sarcoma with endobronchial metastasis. A 28-year-old man had recurrent pneumothorax and underwent wedge resection. He presented at our hospital with hemoptysis, dyspnea, and chest pain. Chest computed tomography revealed left pneumothorax, multiple lung nodules and endobronchial lesions at the right lower basal lobe. Bronchoscopy showed a hemorrhagic mass obstructing the bronchus of the right lower basal lobe. Magnetic resonance imaging revealed multiple nodular lesions in the left thigh muscles. The bronchoscopic biopsy of the endobronchial lesion and the muscle biopsy of the thigh showed the same feature epithelioid sarcoma. This is the first case report of an epithelioid sarcoma with endobronchial metastasis that was diagnosed by bronchoscopic biopsy.
MeSH Terms
Figure
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Figure 1 Chest computed tomography. (A) The arrows indicate the endobronchial lesion of right lower lung basalis bronchus. CT shows multiple lung nodules at both lung and left pneumothorax. (B) After chemotherapy, the endobronchial lesion is disappeared.
Figure 2 Fiberobronchoscopic photography showing a endobronchial mass at the orifice of the right lower lobe basalis bronchus. RML: right middle lobe, RLL: right lower lobe.
Figure 3 (A) Bronchoscopic biopsy specimen. (B) Muscle biopsy specimen. The specimens were composed of relatively uniform, polygonal or epithelioid cells with abundant, deeply eosinophilic cytoplasm (Hematoxylineosin, original magnification ×400).
Figure 4 Immunohistochemistry stain by Vimentin (A), Cytokeratin (B), Epithelial Membrane Antigen (C), and CD34 (D) in bronchoscopic biopsy specimen (original magnification ×400).
Reference
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