Ultrasonography.  2014 Apr;33(2):136-142.

Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease

• Kim SY
• Woo S
• Hwang SI
• Moon MH
• Sung CK
• Lee HJ
• Cho JY
• Kim SH

Abstract

PURPOSE
The aim of this study was to explore the usefulness of the resistive index (RI) on spectral Doppler ultrasonography (US) in the detection of renal cell carcinoma (RCC) in patients with end-stage renal disease (ESRD).
METHODS
Seventeen ESRD patients with kidneys in which renal masses were suspected in routine US were subjected. They underwent computed tomography scans and additional Doppler US for the characterization of the detected lesions. All underwent radical nephrectomy with the suspicion of RCC. Fourteen patients finally were included. RI measurements were conducted in the region of the suspected renal mass and the background renal parenchyma. The intraclass correlation coefficient was used to assess the reproducibility of the RI measurement. A paired t-test was used to compare the RI values between the renal mass and the background renal parenchyma (P<0.05).
RESULTS
The RI values measured at the RCCs were significantly lower than those measured at the background renal parenchyma (0.41-0.65 vs. 0.75-0.89; P<0.001). The intrareader reproducibility proved to be excellent and good for the renal masses and the parenchyma, respectively (P<0.001).
CONCLUSION
RI on spectral Doppler US is useful in detecting RCC in patients with ESRD. The RI values measured at the RCCs were significantly lower than those measured at the background renal parenchyma.

Keyword

Ultrasonography, Doppler, pulsed; Ultrasonography, Doppler, color; Kidney failure, chronic; Carcinoma, renal cell

MeSH Terms

Carcinoma, Renal Cell*
Humans
Kidney
Kidney Failure, Chronic*
Nephrectomy
Ultrasonography, Doppler*
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Pulsed