Tuberc Respir Dis.  2008 Nov;65(5):385-389.

Correlation between Caloric Intake and Lung Function Parameters in Patients with Chronic Obstructive Pulmonary Disease

• Yoon HI
• Park YM
• Choue R
• Kang YA
• Kwon SY
• Lee JH
• Lee CT

Abstract

BACKGROUND: There are reports that food deprivation causes emphysematous changes in the lungs of rats and humans. However, the meaning of this phenomenon in patients with chronic obstructive pulmonary disease has not been evaluated. The aim of this study was to determine the correlations between the caloric intake and parameters of the lung function in patients with chronic obstructive pulmonary disease.
METHODS
Patients with chronic obstructive pulmonary disease who had visited the respiratory clinic from March, 2006 for one year were enrolled in this study. The patients underwent pulmonary function tests, and a dietitian evaluated their nutritional intake using a food record method.
RESULTS
There was no correlation between the total caloric intake and forced vital capacity (FVC, %predicted) or forced expiratory volume in one second (FEV1, %predicted). The total caloric intake showed a positive correlation with the diffusing capacity of carbon monoxide (DLCO %predicted, DLCO/VA %predicted), and a negative correlation with the total lung capacity (TLC, %predicted). Of the calories taken, only calories from protein intake correlated with the diffusing capacity of carbon monoxide (DLCO %predicted, DLCO/VA %predicted).
CONCLUSION
The total caloric intake of patients with chronic obstructive pulmonary disease showed a positive correlation with the diffusing capacity of the lung, and a negative correlation with the total lung capacity. Further study on the linkage between the caloric intake and severity of emphysema is needed.

Keyword

Chronic obstructive pulmonary disease; Nutrition; Emphysema; Energy intake; Lung function

MeSH Terms

Animals
Carbon Monoxide
Emphysema
Energy Intake
Food Deprivation
Forced Expiratory Volume
Humans
Lung
Pulmonary Disease, Chronic Obstructive
Rats
Respiratory Function Tests
Total Lung Capacity
Vital Capacity
Carbon Monoxide

Figure

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  Figure 1 Correlation between total caloric intake and parameters of pulmonary function. r: Pearson's correlation coefficient.

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