Tuberc Respir Dis.  2005 Dec;59(6):679-683.

A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma

Affiliations
  • 1Department of Internal medicine, Presbyterian Medical Center, Jeonju, Korea. drnbear@gmail.com
  • 2Department of Internal medicine, Chonbuk National University Medical School, Korea.
  • 3Kim kwiwan Medical Clinic, Jeonju, Korea.

Abstract

Cancer associated retinopathy (CAR) syndrome is a very rare ocular manifestation of paraneoplastic syndrome, and is characterized clinically by progressive visual impairment. Immune cross-reactivity between antigens in the cancerous tissue and antigens in the retina may play an important role in its pathogenesis, and most of cases are associated with lung carcinoma, particularly small cell lung cancer. The clinical triad of CAR is described as photosensitivity, ring scotomata, and an attenuated retinal arterial caliber. Here, we report a 61-year old male patient with CAR syndrome, who had small cell lung carcinoma in the stage of limited disease, with a brief review of the relevant literature.

Keyword

Cancer associated retinopathy; CAR syndrome; Paraneoplastic syndrome; Small cell lung cancer

MeSH Terms

Humans
Lung
Male
Middle Aged
Paraneoplastic Syndromes
Paraneoplastic Syndromes, Ocular*
Retina
Retinaldehyde
Small Cell Lung Carcinoma*
Vision Disorders
Retinaldehyde
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