Tuberc Respir Dis.  2003 Dec;55(6):579-588.

Clinical usefulness of Clinical Pulmonary Infection Score of ICU Patients with Sputum Culture positive for Multi-drug resistant Acinetobacter baumannii

• Lee JH
• Cheon SC
• Jung SH
• Phyun LH
• Jang MZ
• Lee SY
• Hong SK
• Hong SG
• Lee JH
• Hong SB

Abstract

BACKGROUND: The hospital-acquired pneumonia is the most common nosocomial infection. Recently, the Acinetobacter baummannii infections are rapidly increasing, especially the frequency of Multi-drug resistant A. baumannii. Therefore we assessed clinical features and prognosis of patients in the ICU with Multi-drug resistant A. baumannii from the sputum culture using the Clinical Pulmonary Infection Score(CPIS).
METHODS
The medical records of 43 patients with Multi-drug resistant A. baumannii from sputum culture who were suspected had clinically pneumonia and admitted to the ICU from January 2000 to July 2002 were retrospectively analyzed. RESULT: 19 patients were CPIS greater than 6 and 24 patients were CPIS less than or equal to 6. Mean age for the former was 71+/-11 years old, and the latter was 61+/-19 years old. The mean APACHE II score on admission and on sputum study was not different between two groups(17.4+/-5.7 vs 18.5+/-6.1, p=0.553, 20+/-6 vs 17+/-8, p=0.078). But the mortality rate was 73.7% for the former, and 16.7% for the latter(p<0.001).
CONCLUSION
In ICU patients who had clinically suspected pneumonia with sputum culture positive for Multi-drug resistant A. baumannii, the mortality was significantly higher if CPIS was greater than 6.

Keyword

Multi-drug resistant Acinetobacter baumannii; Hospital acquired pneumonia; Clinical Pulmonary Infection Score (CPIS)

MeSH Terms

Acinetobacter baumannii*
Acinetobacter*
APACHE
Cross Infection
Humans
Medical Records
Mortality
Pneumonia
Prognosis
Retrospective Studies
Sputum*