Sleep Med Psychophysiol.
1999 Dec;6(2):110-115.
The Effect of Mandibular Repositioning Device on Airway Size and Airway Collapsibility in Obstructive Sleep Apnea Syndrome: Cine CT during Sleep
- Affiliations
-
- 1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 2Department of Orthodontics, Institute of Oral Health, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 3Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 4Department of Ortorhinolaryngology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 5Department of Neurology, Anyang General Hopital, Anyang, Korea.
- 6Department of Orthodontics, College of Dentistry, Yonsei University, Seoul, Korea.
Abstract
OBJECTIVES
To investigate the effect of mandibular repasitioning device on airway sige and airway collapsibility in patients with obstructive sleep apnea syndrome (OSAS).
METHODS
Cine CT with polysomnographic monitoring was performed during sleep in nine (OSAS) patients before and after mandibular repositioning device (MRD) application. Axial CT images were obtained in five upper airway levels (retropalatal-high, retropalatal-low, retroglossal, epiglottis, and hypopharynx levels). In each airway level, one axial CT image was obtained during sleep apnea period and 10 serial axial CT images were scanned every 1 second during normal sleep breathing. After wearing MRD, all CT images were obtained by the same method. The cross-sectional areas of airway were measured by automatic tracing method. The changes of minimum airway size and maximum airway size after MRD were evaluated. The airway collapsibility was calculated before and after MRD.
RESULTS
During sleep apnea, the airway of retropalatal-low level was the most frequently narrowest site. During normal sleep breathing the minimum airway size was increased significantly after MRD at retropalatal-low level (p=0.011). The mean airway collapsibility was the highest at retropalatal-low level. MRD decreased the airway collapsibility significantly at retropalatal-low level (p=0.021) and epiglottis level (p=0.038).
CONCLUSIONS
The enlargement of the minimum airway size and decreased airway collapsibility may be the therapeutic mechanism of MRD in obstructive sleep apnea.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Upper airway studies in patients with obstructive sleep apnea syndrome
- The Role of Endothelin-1 in Obstructive Sleep Apnea Syndrome and Pulmonary Hypertension
- Airway Narrowing Patterns during Obstructive Sleep Apnea: Airway CT and Multi-level Airway Pressure Monitoring
- Effects of the Body Position Changes on Upper Airway Caliber in Obstructive Sleep Apnea during Sleep
- Two Cases of Pediatric Obstructive Hypoventilation Managed with Upper Airway Surgery
