Korean J Urol.  2011 Jun;52(6):425-427.

Miliary Tuberculosis Following Transrectal Ultrasonography (TRUS)-Guided Prostate Biopsy

Affiliations
  • 1Department of Urology, Kohka Public Hospital, Kohka, Japan. cj-kim@belle.shiga-med.ac.jp

Abstract

Miliary tuberculosis (TB) after transrectal ultrasonography (TRUS)-guided prostate biopsy is an extremely rare complication. A 75-year-old patient who presented with high fever and cough following TRUS-guided prostate biopsy for his high serum prostate-specific antigen (PSA) level (13.104 ng/ml) was diagnosed with miliary TB after clinical, laboratory, and radiological assessments. Histopathological examination of the prostate revealed TB with acid-fast bacilli. He was treated with chemotherapy for 9 months. The patient is now symptom-free, and his post-treatment PSA level was 5.023 ng/ml. This case is reported to acknowledge the possibility that miliary TB can occur as a complication of prostate biopsy if the patient suffers from prostate TB.

Keyword

Biopsy; Complications; Miliary tuberculosis; Prostate; Tuberculosis

MeSH Terms

Aged
Biopsy
Cough
Fever
Humans
Prostate
Prostate-Specific Antigen
Tuberculosis
Tuberculosis, Miliary
Prostate-Specific Antigen

Figure

  • FIG. 1 Hypoechoic lesion in the left peripheral zone of the prostate by transrectal ultrasonography.

  • FIG. 2 Chest CT scan showing multiple nodular and macular shadows with pleural effusions in bilateral lungs.

  • FIG. 3 Caseous necrosis rimmed with some epithelioid cells and Langhans' type giant cells (H&E, ×100).


Reference

1. Berger AP, Gozzi C, Steiner H, Frauscher F, Varkarakis J, Rogatsch H, et al. Complication rate of transrectal ultrasound guided prostate biopsy: a comparison among 3 protocols with 6, 10 and 15 cores. J Urol. 2004. 171:1478–1480.
2. Djavan B, Waldert M, Zlotta A, Dobronski P, Seitz C, Remzi M, et al. Safety and morbidity of first and repeat transrectal ultrasound guided prostate needle biopsies: results of a prospective European prostate cancer detection study. J Urol. 2001. 166:856–860.
3. Fong IW, Struthers N, Honey RJ, Simbul M, Boisseau DA. A randomized comparative study of the prophylactic use of trimethoprim-sulfamethoxazole versus netilmycin-metronidazole in transrectal prostatic biopsy. J Urol. 1991. 146:794–797.
4. Aus G, Ahlgren G, Bergdahl S, Hugosson J. Infection after transrectal core biopsies of the prostate--risk factors and antibiotic prophylaxis. Br J Urol. 1996. 77:851–855.
5. Rietbergen JB, Kruger AE, Kranse R, Schröder FH. Complications of transrectal ultrasound-guided systematic sextant biopsies of the prostate: evaluation of complication rates and risk factors within a population-based screening program. Urology. 1997. 49:875–880.
6. Norberg M, Holmberg L, Häggman M, Magnusson A. Determinants of complications after multiple transrectal core biopsies of the prostate. Eur Radiol. 1996. 6:457–461.
7. Jeon SS, Woo SH, Hyun JH, Choi HY, Chai SE. Bisacodyl rectal preparation can decrease infectious complications of transrectal ultrasound-guided prostate biopsy. Urology. 2003. 62:461–466.
8. McAleer SJ, Johnson CW, Johnson WD. Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Tuberculosis and parasitic and fungal infections of the genitourinary system. Campbell-Walsh urology. 2007. 9th ed. Philadelphia: Saunders;436–470.
9. Lee Y, Huang W, Huang J, Wang J, Yu C, Jiaan B, et al. Efficacy of chemotherapy for prostatic tuberculosis - a clinical and histologic follow-up study. Urology. 2001. 57:872–877.
10. Sporer A, Auerbach O. Tuberculosis of prostate. Urology. 1978. 11:362–365.
Full Text Links
  • KJU
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr