Korean J Urol.  2011 Jun;52(6):416-420.

Correlation between Serum Total Testosterone and the AMS and IIEF Questionnaires in Patients with Erectile Dysfunction with Testosterone Deficiency Syndrome

• Kang JI
• Ham BK
• Oh MM
• Kim JJ
• Moon DG

Abstract

PURPOSE
This study was conducted to investigate the relationship between serum total testosterone levels and scores on the Aging Male's Symptom (AMS) scale and the International Index of Erectile Function (IIEF) in men with erectile dysfunction with testosterone deficiency syndrome (TDS).
MATERIALS AND METHODS
From January 2005 to July 2008, 134 patients who complained of sexual dysfunction such as erectile dysfunction or decreased libido as the main symptoms of TDS with serum total testosterone levels less than 3.5 ng/ml were evaluated by independent t-test and linear regression analysis, respectively. Patients with treated hypogonadism within 6 months, with a history of taking a PDE5 inhibitor or an antidepressant for a depressive disorder, or who had metabolic syndrome were excluded from this study.
RESULTS
The AMS scale and its 3 subdomain scores were not significantly correlated with the total testosterone level. By contrast, the total IIEF score and the score of each IIEF domain except sexual desire showed a weakly significantly positive correlation with serum total testosterone.
CONCLUSIONS
In TDS patients with erectile dysfunction, there was a low relationship between serum total testosterone levels and the AMS scale and a weakly positive correlation between total testosterone levels and all IIEF domains except sexual desire. There was a low relationship between the AMS scale, the sexual desire domain score of the IIEF, and total testosterone. We should understand these limitations when evaluating patients with erectile dysfunction with TDS. New scales should be developed for the evaluation of erectile dysfunction in these patients.

Keyword

Erectile dysfunction; Questionnaires; Testosterone

MeSH Terms

Aging
Depressive Disorder
Erectile Dysfunction
Humans
Hypogonadism
Libido
Linear Models
Male
Sorbitol
Testosterone
Tyramine
Weights and Measures
Sorbitol
Testosterone
Tyramine

Figure

• 

  FIG. 1 Correlation of serum total testosterone and IIEF scores. TT: total testosterone, IIEF: International Index of Erectile Function.

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